NAME: L-thyroxine
SYNONYM(s): Levothyroxine; T4(hormone); 3,3',5,5'-tetraiodo-L-thyronine
IMIS: L200
CAS: 51-48-9
NIOSH: YP283350
DESCRIPTION: off-white to cream crystalline powder which is odorless
MW: 776.87
MOLFM: C15H11I4NO4
MP: 235-236º C (decomposes)
Exposure Limits
Health Factors
SYMPTOM(s): acute irritant to skin, eyes, mucous membranes, and respiratory system; nervousness; sweating; hyperhydrosis; tachycardia; angina pectoris
HEALTH EFFECTS: acute irritant to skin, eyes, mucous membranes, and respiratory system
ORGAN: skin, eyes, respiratory system, mucous membranes
Monitoring
PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):
MEDIA: Glass Fiber Filter (37 mm) in 3-piece cassette
ANL SOLVENT: Methanol
MAX V: 480 Liters MAX F: 2.0 L/min MIN F: 1.0 L/min MAX T: 240 Minutes
ANL 1: High Performance Liquid Chromatography; HPLC/UV at 230nm
REF: 2 (OSHA In-House File) CLASS: Not Validated
COND: Column C18 Mobile Phase: 80/20 MeOH/H2O .2% H3PO4
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